Clinical Immunology

The Clinical Immunology research groups have a strong translational focus. The research projects aim to increase the understanding about immunological mechanisms in patients with cancer or autoimmune disease (diabetes, rheumatoid arthritis, systemic lupus erythematosus or multiple sclerosis) and to explain the immune reactions that occur when immune cells or components come in contact with biomaterial, transplanted organs, cells or viruses used for therapy.

Within this research area we are developing novel immune, gene and cell therapies as well as diagnostic/prognostic markers, which are tested in clinical trials in collaboration with Uppsala University Hospital, other national and international universities, the immune diagnostic industry, EU networks and the Nordic Network for Islet Transplantation.
 

Research groups

• Magnus Essand – Gene, cell and immunotherapy of cancer
   
• Olle Korsgren – Diabetes research
   
• Angelica Loskog  – Immunotherapy for cancer and autoimmune diseases
   
• Yumeng Mao – Dissecting the negative immune regulatory network to improve cancer immunotherapy
   
• Bo Nilsson – Adverse activation of the cascade systems and cells of the blood during cell therapy or treatment with biomaterials
   
• Johan Rönnelid – Immune complexes in rheumatic diseases
   
• Maria Ulvmar – Stromal cell mediated immune regulation in the lymph node