Research and education at IGP
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Recent research papers from IGP
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Koning, Harmen Kornelis; Ahemaiti, Aikeremu; Boije, Henrik
A deep-dive into fictive locomotion - a strategy to probe cellular activity during speed transitions in fictively swimming zebrafish larvae
2022
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Barbera, Stefano; Cucini, Claudio
A glimpse into the past: phylogenesis and protein domain analysis of the group XIV of C-type lectins in vertebrates
2022
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Zhao, Linxuan; Polavarapu, Vamsi Krishna; Yadav, Ram Prakash; Xing, Pengwei; Chen, Xingqi
A Highly Sensitive Method to Efficiently Profile the Histone Modifications of FFPE Samples
2022
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Liu, Jun; de Vries, Paul S.; Del Greco, Fabiola M.; Johansson, Åsa; Schraut, Katharina E.; Hayward, Caroline; van Dijk, Ko Willems; Franco, Oscar H.; Hicks, Andrew A.; Vitart, Veronique; Rudan, Igor; Campbell, Harry; Polasek, Ozren; Pramstaller, Peter P.; Wilson, James F.; Gyllensten, Ulf; van Duijn, Cornelia M.; Dehghan, Abbas; Demirkan, Ayse
A multi-omics study of circulating phospholipid markers of blood pressure
2022
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Habicher, Judith; Manuel, Remy; Pedroni, Andrea; Ferebee, Charles; Ampatzis, Konstantinos; Boije, Henrik
A new transgenic reporter line reveals expression of protocadherin 9 at a cellular level within the zebrafish central nervous system
2022
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Ceder, Mikaela M.; Fredriksson, Robert
A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies
2022
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Gao, Menghan; Yngve, Erik; Yu, Di; Jin, Chuan
A qPCR-Based Method for Quantification of RCA Contaminants in Oncolytic Adenovirus Products
2022
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Lagerstedt-Robinson, Kristina; Baranowska Korberg, Izabella; Tsiaprazis, Stefanos; Bjorck, Erik; Tham, Emma; Poluha, Anna; Hellstrom Pigg, Maritta; Paulsson-Karlsson, Ylva; Nordenskjold, Magnus; Johansson-Soller, Maria; Aravidis, Christos
A retrospective two centre study of Birt-Hogg-Dube syndrome reveals a pathogenic founder mutation in FLCN in the Swedish population
2022
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Adler, Anna; Manivel, Vivek Anand; Fromell, Karin; Teramura, Yuji; Nilsson Ekdahl, Kristina; Nilsson, Bo
A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein
2022
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Berglund, Eva Caroline; Barbany, Gisela; Orsmark-Pietras, Christina; Fogelstrand, Linda; Abrahamsson, Jonas; Golovleva, Irina; Hallböök, Helene; Höglund, Martin; Lazarevic, Vladimir; Levin, Lars-Ake; Nordlund, Jessica; Noren-Nystrom, Ulrika; Palle, Josefine; Thangavelu, Tharshini; Palmqvist, Lars; Wirta, Valtteri; Cavelier, Lucia; Fioretos, Thoas; Rosenquist, Richard
A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias
2022
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
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Oral contraceptives and hormone treatment increase stroke risk
2022-06-27
A new study from IGP show that oral contraceptives and also hormone replacement therapy at menopause increase the risk of stroke. The increased risk was largest during the first year of treatment, after which it declined. The study, which is now published in the journal Stroke, is based on data from more than a quarter of a million women from the database UK Biobank.
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Rare genetic variants are not the main cause of common diseases
2022-05-13
Although some rare variants can significantly increase the risk of disease for a few individuals, the majority of the genetic contribution to common diseases is due to a combination of many common genetic variants with small effects. This is shown by researchers at IGP and other departments at Uppsala University in a new comprehensive study published in the journal Nature Communications.
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Subgroups of brain tumours associated with cell origin and disease prognosis
2022-04-25
Researchers at IGP have detected different subgroups of the brain tumour form glioblastoma, where the cancer cells’ properties depend on which cell type they originate from. The used analysis method could also separate glioblastoma patients with significant differences in survival. The findings open up for identifying specific therapeutic targets for the new subgroups of glioblastoma.